Hi-Tech Pharmaceuticals Synadrene 45 Caps

Hi-Tech Pharmaceuticals Synadrene 45 Caps

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Hi-Tech Pharmaceuticals Synadrene 45 Caps

If you’re looking for Synedrex, this is the ideal replacement.

Synadrene was developed by Hi-Tech Pharmaceuticals as an alternative to Metabolic Nutrition’s Synedrex. The version of Synedrex that was previously available is being reformulated and it is no longer available to purchase anywhere, or is being sold at a very high price. Chances are we won’t see the reformulated version for a while, and they are most likely removing the active ingredient AMP Citrate. Synadrene is a formula that is closer to the original Synedrex and uses the power of 1,3 DMAA.

How Does This Compare?

There were 3 different versions of Synedrex in the past. The first version of Synedrex used 1,3 DMAA. The second version just had caffeine. The third and most recent version used AMP Citrate. Synadrene by Hi-Tech is using 1,3 DMAA again, which was the active ingredient in the original Synedrex. So you’re actually getting a better product that is stronger and closer to the original Synedrex formula.

Benefits & Results

  • Thermogenic fat burning

  • Boosts energy levels

  • Improved mood and focus

  • Stops hunger

Questions About Synadrene

Can women use this?

Yes, this product can be used by both men and women. This product is non-hormonal so it is safe for women.

Can I stack this product?

You shouldn’t stack it with other products containing stimulants, but we recommend using it with Thyrene or Hydravax, which are both non/low stimulant. For those wanting to take it pre-workout, you can stack it with non-stimulant pre-workout supplements.

Can I take this with my pre-workout?

Yes, if you are using a non-stimulant pre-workout formula.

Is it gluten free?


How much caffeine is in it?

100 mg per capsule.

How much 1,3 DMAA is in it?

While they don't list the actual amount, it is estimated at 25mg per capsule.

How does Synadrene compare to Stimerex and Stimerex Hardcore?

Stimerex will have more of a range of different stimulants. Not as much DMAA and added Ephedra Extract. With Stimerex Hardcore, it has more caffeine (150mg) and added ephedra extract. Both Stimerex formulas are more for an energy kick and weight loss, rather than just focusing on weight loss.

How does Synadrene compare to Lipodrene and Lipodrene Hardcore?

The biggest difference between the two is that Lipodrene has ephedra extract. Synadrene does not. Though Synadrene supposely does have more DMAA than both formulas of Lipodrene.

Directions & Dosage

Hi-Tech Pharmaceuticals recommends that you start by taking one capsule per day. Take on an empty stomach. Once you know how you respond to one capsule, you can move up to 2 a day if you wish. The best results will be seen when conforming to a diet and exercise program. You should also make sure to get an adequate amount of rest each night. Do not take Synadrene within 4 hours of when you go to bed.


Synadrene is a very strong weight loss supplement, and you should not stack it with any other stimulants. There are other products it can be stacked with:

  • Thyrene - This is a product that can improve thyroid function to promote weight loss and a fast metabolism.

  • Hydravax - This is a diuretic that can help with excess water weight and stop bloating. You will see more definition and get results easier.

Ingredients & Supplement Facts

Servings Per Bottle: 45
Serving Size: 1 Capsule

Vitamin B3 (as Niacin): 20mg
Vitamin B6 (as Pyridoxine HCL): 4.25mg
Vitamin B12 (as Cyanocobalamin): 100mcg
Chromium: 175mcg

Synedrex Formulated Weight Loss Solution Blend: 920mg
Methylxanthine: *
1,3 Dimethylamylamine HCL: *
Sulbutiamine: *
Sandalwood Extract: *
Yohimbine Extract: *
Alpha Lipoic Acid: *
Poly-liodo-Thyonine: *

Other Ingredients: DiPotassium Phosphate, MCMC, Silicone Dioxide, Magnesium Stearate, Titanium Dioxide, FD & C Blue 1, Red 40, Ti02, Gelatin

Warnings & Side Effects

Do not exceed the recommended dose. This product should only be used by healthy adults at least 21 years old. Do no use if pregnant or nursing, or if you are at risk of, or being treated for diabetes, liver problems, prostate enlargement, anxiety, depression, seizure disorder, stroke or high blood pressure. Consult your health care professional before using any dietary supplements.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, cure, diagnose, or prevent any disease.This product should not be used in place of or as a substitute for recommendations by your healthcare professional. No clinical study has been performed on Synadrene™. These statements are based upon the active ingredients: 1,3 dimethylamylamine, Caffeine, Yohimbine, Sandalwood extract, Sulbutiamine, and green tea extract. WARNING: this product can raise your blood pressure and interfere with other drugs you may be taking. Talk to your doctor about this product.

Ask a Question

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Questions on Hi-Tech Pharmaceuticals Synadrene 45 Caps

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  • From Brooke at Sep/23/00002016 04:September PM
    • How does this product compare to stimerex hardcore?
    • Stimerex Hardcore has 150mg of caffeine, which is about 50mg more than the Synadrene. It also has ephedra extract. On the other hand, this product should have more DMAA than Stimerex Hardcore. Thinking about one or the other? The Stimerex Hardcore is more for people that want to 'feel' it working...the warming sensation and energy kick. Hope this helps!
  • From Kim at Sep/25/00002016 04:September PM
    • How much DMAA is contained in this product per dose?
    • It is part of a proprietary blend so we do not know the exact dosage of DMAA. Due to take 1 capsule 3x per day, we would estimate 20-25mg of DMAA per capsule in Synadrene. Some of the other products Hi Tech Pharmaceuticals makes as well have this similar dosage of DMAA per capsule.
  • From Michelle at Oct/03/00002016 03:October AM
    • I thought 1, 3 DMAA was banned???
    • It used to be banned, but Hi Tech Pharmaceuticals fought the government last year and won. They are now the only company that can sell and/or manufacturer the ingredient. So in the USA it is completely legal now. And instead of using AMP Citrate in this product, they replaced it with DMAA, which makes it identical to the ORIGINAL Synedrex from a few years ago (pre-ban).

Customer Reviews


Customer Reviews

Working well so far Review by Aimee M
Recommend to a Friend
Use Again
Total Rating
Seems to be working just like the Synedrex I had before. I literally ran out, bought this, got it in 2 days and started it...didn't even miss a day :-) The big difference is in the energy. It is stronger. Hoping the weight loss continues too. Miss my Syny...but seems like this will do the job :-) (Posted on MMMMMMMMMMMM 04, 16)
Would you recommend this product to a friend? Likely

great stuff Review by Lane
Use Again
Total Rating
Recommend to a Friend
This product by Hi-tech pharmaceuticals is a good dual purpose supplement. One purpose of this supplement is that it can help you get some really good energy. I does have DMAA, which is awesome because that gives you some really amazing energy. It was sort of banned for a little while, but it is not anymore and I am glad. Another purpose of this supplement is for fat loss. That is the main purpose, but you will not lose a ton from this. It will help though. (Posted on MMMMMMMMMMMM 26, 16)
Would you recommend this product to a friend? Likely

First to Try Review by Brian
Recommend to a Friend
Use Again
Total Rating
I was given a sample packet of the Synadrene to test out before it's release. I have used Synedrex for years, so I was excited to get to be one of the first to try it out. Now I am not looking to lose weight, but wanted to see how it worked energy wise compared to Metabolic's Synedrex. Well this stuff hits just as hard, possibly even harder. I love 1,3 DMAA and this stuff uses that instead of the AMP Citrate. Now I still like AMP Citrate, but the issue I had was it seemed by body got used to it really quick. Not this...I took it for 4 days straight and it made me feel great and energized each and every day I took it. No crash and energy lasted for a good 4+ hours, so maybe not the best thing to take right before bed...but worked great for early morning work and then for pre-workout as well. I think everyone is going to love this product. (Posted on MMMMMMMMMMMM 23, 16)
Would you recommend this product to a friend? Definitely yes

Staff Reviews

Jeff Moriarty - This just arrived to our warehouse on Sept 28th, and I was one of the first to bust into a bottle. I have taken Synedrex many times in the past, so was excited to see how this product compared to it. The first thing I noticed was how much smaller the bottle was. It's like a miniture Synedrex. But still has the 45 capsules, just like it. Now looking at the ingredients, Hi Tech definitely stepped up the ingredients. In addition to the 1,3 DMAA, there is more of many of the ingredients, so it's going to hit you harder. Within about 15min of taking Synadrene I could feel it working. A little warmer and more energized. Nothing crazy, as I am used to DMAA, but I knew what to expect and this delivered. And this was after taking just one capsule. I will definitely miss Synedrex, but this more than makes up for it. Hi Tech definitely was smart in getting a replacement out asap. I really think Metabolic Nutrition dropped the ball. They should have had another version ready after the latest was discontinued. I think there will always be a market for the Synedrex, but as more time goes by and people can't find it anywhere, Synadrene will be the permanent replacement.

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