Trimethylglycine (TMG) is also called glycine betaine, but the name trimethylglycine signifies that it has three methyl groups attached to each molecule of glycine. TMG was discovered to be beneficial to heart health back in the 1950s.(101-105)

TMG operates along a pathway similar to that of vitamin B12: It is a "methyl donor," providing extra methyl groups to hasten the conversion of homocysteine back to methionine.(106) When a TMG methyl group is donated to a molecule of homocysteine, it converts to the non-toxic amino acid, methionine.(107,108)

Research showing TMGs ability to promote healthy levels of homocysteine, alone or in conjunction with other nutrients, confirms its status as an important nutrient for supporting cardiovascular health.(109-117) For example, in a recent cross-sectional survey study, participants who consumed >360mg/d of TMG had, on average, 10% lower concentrations of homocysteine and 19% lower concentrations of C-reactive protein than did those who consumed <260mg/d.(118)

Supplement Facts
2 tablets contain:
Calcium (as dicalcium phosphate) 85mg
Phosphorus (as dicalcium phosphate) 65mg
Trimethylglycine (TMG) 1000mg
---(as betaine anhydrous)

Other ingredients: dicalcium phosphate, microcrystalline cellulose, stearic acid, croscarmellose sodium, vegetable stearate, silicon dioxide, aqueous film coating (purified water, hydroxypropyl methylcellulose, natural wax, glycerin).

Contains NO: soybeans, milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), tree nuts, wheat, yeast, gluten, corn, or rice. Contains NO artificial sweeteners, flavors, colors, or preservatives.

Directions:
Adults: Take two tablets in the morning with or without food, or as recommended by a healthcare practitioner. TMG should be taken with co-factors vitamins B6, B12, and folic acid.

Warnings:
If muscle tension or headaches occur, reduce dose or discontinue product, and inform your physician if they do not subside. If you are pregnant, nursing, or undergoing treatment for a medical condition, please consult your healthcare professional before using this product. Keep out of the reach of children.