
Jarrow Pantethine 450mg 60 Softgels


Panthine is a nutritional supplement related to Vitamin B5 which is often used to help lower cholesterol levels and triglycerides in people suffering from diabetes. Each softgel of Jarrow's Pantethine contains 450mg of Pantethine.
Take 1 softgel per day with a meal.
Store in a cool dry place after opening. If you have a medical condition or if adverse reactions occur discontinue use immediately.
Rumberger JA, Napolitano J, Azumano I, Kamiya T, Evans M. Pantethine, a derivative of vitamin B(5) used as a nutritional supplement, favorably alters low-density lipoprotein cholesterol metabolism in low- to moderate-cardiovascular risk North American subjects: a triple-blinded placebo and diet-controlled investigation. Nutr Res. 2011 Aug;31(8):608-15. doi: 10.1016/j.nutres.2011.08.001. PMID: 21925346.
https://pubmed.ncbi.nlm.nih.gov/21925346/
Brunetti D, Dusi S, Giordano C, Lamperti C, Morbin M, Fugnanesi V, Marchet S, Fagiolari G, Sibon O, Moggio M, d'Amati G, Tiranti V. Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model. Brain. 2014 Jan;137(Pt 1):57-68. doi: 10.1093/brain/awt325. Epub 2013 Dec 6. PMID: 24316510; PMCID: PMC3891449.
https://pubmed.ncbi.nlm.nih.gov/24316510/
Wittwer CT, Gahl WA, Butler JD, Zatz M, Thoene JG. Metabolism of pantethine in cystinosis. J Clin Invest. 1985 Oct;76(4):1665-72. doi: 10.1172/JCI112152. PMID: 4056044; PMCID: PMC424158.