Life Extension 5-LOXIN 75mg 100 Vege Caps
5-lipoxygenase (5-LOX) is a member of the lipoxy-genase family of enzymes. It transforms fatty acids into leukotrienes. Excess levels of the enzyme 5-LOX sets in motion inflammatory responses that have been linked to common degenerative effects in aging individuals.
Normal aging results in higher-than-desired levels of 5-LOX.
The typical American diet adds to the danger. Foods rich in omega-6 fatty acids like red meat, poultry, eggs and dairy products, along with high-glycemic carbohydrates, trigger overproduction of arachidonic acid. In response to high levels of arachidonic acid, the body produces the 5-LOX enzyme.
5-LOX breaks down arachidonic acid to pro-inflammatory compounds like leukotriene B4,14 a molecule that mediates attacks to joints, arterial walls, and other tissues. 5-LOX itself facilitates undesirable cell division changes.
The good news is that an extract of the Indian plant Boswellia serrata has been shown to neutralize 5-LOX. Used for centuries to help with inflammatory issues, boswellia acts as a natural 5-LOX inhibitor, intervening at the cellular level to block its unwanted effects. Confirmatory data reveal that a compound contained in boswellia called AKBA (3-O-acetyl-11-keto-ß-boswellic acid)17,18 is the key to its beneficial action.