Life Extension Bromelain works very well if taken twice a day, 1/2 - 1 hour before breakfast, and 1 at bedtime (an hour after dinner). It will take a month or 2 to show best results, but it does contribute to weight loss. I combined it with regular exercise and sensible eating and lost several pounds (and 2 dress sizes) over a few months. Be patient at first. NOTE: You need to take the Enterically Coated version of Bromelein though, as this works best. You can't get this version in Canada though, so it needs to be ordered in the U.S.