Skip to content

Hi-Tech Pharmaceuticals Synadrene 45 Capsules

58 reviews   |  
Original price $69.95
Original price $69.95 - Original price $69.95
Original price $69.95
Current price $39.95
$39.95 - $39.95
Current price $39.95
SKU 811836022360
Free USA Shipping

Hi-Tech Pharmaceuticals Synadrene 45 Caps

Synadrene was developed by Hi-Tech Pharmaceuticals as an alternative to Metabolic Nutrition’s Synedrex. The version of Synedrex that was previously available is being reformulated and it is no longer available to purchase anywhere, or is being sold at a very high price. Chances are we won’t see the reformulated version for a while, and they are most likely removing the active ingredient AMP Citrate. Synadrene is a formula that is closer to the original Synedrex and uses the power of DMHA.

How Does This Compare?

There were 3 different versions of Synedrex in the past. The first version of Synedrex used 1,3 DMAA. The second version just had caffeine. The third and most recent version used AMP Citrate. Synadrene by Hi-Tech is using DMHA, which was like the active ingredient in the original Synedrex. So you’re actually getting a better product that is stronger and closer to the original Synedrex formula.

Benefits & Results

  • Thermogenic fat burning

  • Boosts energy levels

  • Improved mood and focus

  • Stops hunger

  • Power of DMHA

If You Like Synadrene You Might Also Like...

If You're Looking for Appetite Suppression You Might Like...

Questions About Synadrene

Can women use this?

Yes, this product can be used by both men and women. This product is non-hormonal so it is safe for women.

Can I stack this product?

You shouldn’t stack it with other products containing stimulants, but we recommend using it with Thyrene or Hydravax, which are both non/low stimulant. For those wanting to take it pre-workout, you can stack it with non-stimulant pre-workout supplements.

Can I take this with my pre-workout?

Yes, if you are using a non-stimulant pre-workout formula.

Is it gluten free?


How much caffeine is in it?

It is part of proprietary blend, so we are unsure.

How much DMHA is in it?

They do not disclose the amount listed.

How does Synadrene compare to Lipodrene and Lipodrene Hardcore?

The biggest difference between the two is that Lipodrene has ephedra extract. Synadrene does not.

Is there Any Reason Someone Shouldn't Use Synadrene?

If you're sensitive to strong stimulants you may not react well to Synadrene. If you're looking for appetite suppression over energy HydroxyElite or OxyElite Pro may be better options for you. If you're sensitive to Yohimbine you may not want to take Synadrene. You should also consult with your doctor if you are pregnant, nursing, or on other medications. 

Directions & Dosage

Hi-Tech Pharmaceuticals recommends that you start by taking one capsule per day. Take on an empty stomach. Once you know how you respond to one capsule, you can move up to 3 a day if you wish. The best results will be seen when conforming to a diet and exercise program. You should also make sure to get an adequate amount of rest each night. Do not take Synadrene within 4 hours of when you go to bed.


Synadrene is a very strong weight loss supplement, and you should not stack it with any other stimulants. There are other products it can be stacked with:

  • Thyrene - This is a product that can improve thyroid function to promote weight loss and a fast metabolism.

  • Hydravax - This is a diuretic that can help with excess water weight and stop bloating. You will see more definition and get results easier.

What Are the Active Ingredients in Hi-Tech Synadrene?

  • Caffeine - Energy, Appetite Suppression, Focus and Thermogenesis
  • Green Tea Extract - Energy, Appetite Suppression & Thermogenesis
  • DMHA - Decrease in Appetite, Increase in Focus, Increase in Energy
  • Walnut Extract - DMHA from Nature
  • Sulbutiamine - Nootropic, Provides Focus and Energy
  • Sandalwood Extract - Supports Muscles
  • Yohimbe Extract - Clean Energy & Increased Thermogenesis
  • Alpha Lipoic Acid - Powerful Antioxidant and Weight Loss Ingredient
  • Poly Thyronine - Increased Metabolism & Curbs Cravings

Ingredients & Supplement Facts

Servings Per Bottle: 45
Serving Size: 1 Capsule

Vitamin B3 (as Niacin): 20mg
Vitamin B6 (as Pyridoxine HCL): 4.25mg
Vitamin B12 (as Cyanocobalamin): 100mcg
Chromium: 175mcg

Synedrex Formulated Weight Loss Solution Blend: 815mg

Caffeine Anhydrous: *
Green Tea Extract (leaves) *
2-Aminoisoheptane HCL *
Walnut Extract (bark)
Sulbutiamine: *
Sandalwood Extract: *
Yohimbine Extract: *
Alpha Lipoic Acid: *
Poly-liodo-Thyonine: *

Other Ingredients: DiPotassium Phosphate, MCMC, Silicone Dioxide, Magnesium Stearate, Titanium Dioxide, FD & C Blue 1, Red 40, Ti02, Gelatin

Warnings & Side Effects

Do not exceed the recommended dose. This product should only be used by healthy adults at least 21 years old. Do no use if pregnant or nursing, or if you are at risk of, or being treated for diabetes, liver problems, prostate enlargement, anxiety, depression, seizure disorder, stroke or high blood pressure. Consult your health care professional before using any dietary supplements.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, cure, diagnose, or prevent any disease.This product should not be used in place of or as a substitute for recommendations by your healthcare professional. No clinical study has been performed on Synadrene™. These statements are based upon the active ingredients: DMHA, Caffeine, Yohimbine, Sandalwood extract, Sulbutiamine, and green tea extract. WARNING: this product can raise your blood pressure and interfere with other drugs you may be taking. Talk to your doctor about this product.


Lobb A. Science of weight loss supplements: compromised by conflicts of interest?. World J Gastroenterol. 2010;16(38):4880-4882. doi:10.3748/wjg.v16.i38.4880

Huntington MK, Shewmake RA. Weight-loss supplements: what is the evidence?. S D Med. 2010;63(6):205-207.

Tabrizi R, Saneei P, Lankarani KB, et al. The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2019;59(16):2688-2696. doi:10.1080/10408398.2018.1507996

Alkhatib A, Seijo M, Larumbe E, Naclerio F. Acute effectiveness of a "fat-loss" product on substrate utilization, perception of hunger, mood state and rate of perceived exertion at rest and during exercise. J Int Soc Sports Nutr. 2015;12:44. Published 2015 Nov 25. doi:10.1186/s12970-015-0105-8

Customer Reviews
4.7 Based on 58 reviews
5 ★
4 ★
3 ★
2 ★
1 ★
100reviewers would recommend this product Write a Review Ask a Question

Thank you for submitting a review!

Your input is very much appreciated. Share it with your friends so they can enjoy it too!

Filter Reviews:
  • Synadrene
  • results
  • energy
  • bottle
  • appetite
  • something
  • cardio
  • pill
  • jitters
  • burner
United States
I recommend this product

A product of promise

I just started taking Synadrene about a week ago, this is a high stimulant fat burner. I take one capsule a day once I wake up or a few hours before my work out and it gives me a great sweat, makes me feel very energized and alive to complete my workout without fatigue or burnout. On a scale of 1-10 (1 being the worst and 10 being the best) I give it a 8 because it’s true to is promise high stimulant fat burner. However if I don’t workout I feel minor jitters, none the less this product is true to it’s word.

  • Who would you recommend this product to? Yes
  • Age? 25
Tina S.
United States United States
I recommend this product

Best Energy Boost

Excellent. Quick acting, with no major crash.

  • Who would you recommend this product to? Those who need help with energy, before a workout
  • Age? 30t
Mayra M.
United States United States
I recommend this product

Great product

I love Synadrene!

  • Age? 42
  • Who would you recommend this product to? Everyone
United States United States
I recommend this product

Happy Customer

I've used Synadrene for years and am SO HAPPY it is back in stock. Those few months without it were awful. I've tried so many similar products and nothing comes close.

  • Who would you recommend this product to? Any adult that needs that extra boost without the crash!
  • Age? 48
United States United States

Found a pill that works!

These pills really do work!!!! I've tried just about everything and its been years since I've found something that works. They definitely curve your appetite. I do get a little jittery but nothing serious. I only take one a day. I would definitely recommend eating something small before you take a pill. I do not work out at all. I would recommend this to anyone. Great product.

  • Who would you recommend this product to? Anyone
  • Age? 41
United States United States

Hit or miss

Some bottles are better than others..

  • Who would you recommend this product to? Anyone
  • Age? 25 and up
United States United States

great product

love this product, helps appetite and burn more fat while working out great energy

  • Who would you recommend this product to? yes
  • Age? 53
Katrina H.
United States United States


I love it! BUT be careful. I only use one per day because anything else will hav me up all night. I appreciate the fact it doesnt make me feel jittery BUT it does help with cravings. Synadrex had me SICK! So glad I found Synadrene. I'm about to order another bottle now!

  • Who would you recommend this product to? someone who has a clean diet but needs help to cut fat
  • Age? 30 and above
United States United States

Great supplements

Overal,l, great energy and to workout and keep up with my 3 kiddos�

  • Age? 41
  • Who would you recommend this product to? Busy Mom, whose staying in shape
Kim F.
United States United States

Energy Booster

I was recommended this product by my ex boss who both him and I used to take Zenadrine years ago when it was very strong. Since then I couldn't find a product similar until he told me about Synadrene. It gives me all the energy I need and more, creates thermal heat the keeps me burning fat and suppresses my appetite which is a plus. It actually boosts my mood as caffeine has that affect on me. I have lost 18 lbs so far without struggling with hunger and low energy to exercise. I definitely recommend it if you require energy to get you through your work outs and need assistance with controlling your appetite.

  • Who would you recommend this product to? Definitely
  • Age? 46
United States United States


Hi! Is it possible for me to trade my bottle of Synadrene for a bottle of Stimerex? I have a trial bottle of Stimerex that I'm loving!!! The seal has not been broken. I just need to switch products. Thanks so much!

  • Age? 30 and above
  • Who would you recommend this product to? everyone
Chrissy H.
United States United States

My fave

First off, this is a great company. They are always stocked and get orders out ASAP. I’ll never order anywhere else. Second, I love synedrene. It’s the most effective burner. One in the am before workout and I’m good for the rest of the day.

  • Who would you recommend this product to? Anyone familiar with burners
  • Age? Anyone active.
United States United States

Great prices and Products!

Love this product. Great energy, focus and appetite suppression. No jitters.

  • Who would you recommend this product to? Adults looking to lose a few pounds, lose fat and gain every and focus.
  • Age? 42
United States United States

Synadrene is exceptional

Product delivers the results it claims

  • Age? 47
  • Who would you recommend this product to? Anyone wanting an effective metabolic supplement
United States United States

Fast service, great price

I had no problem ordering this item. It was shipped fast Thank you

  • Age? 30
  • Who would you recommend this product to? Students
Lisa K.
United States United States

Hi -Tech Pharmaceuticals Synadrene

It helps my cravings a lot.

  • Who would you recommend this product to? Anyone who needs to control there appetite
  • Age? 55
United States United States

Great price for great pills

They work amazing

  • Who would you recommend this product to? Yes
  • Age? 24
Shannon H.
United States United States


Love the energy it gives me. I'm not jittery and it curbs my appetite. Helps me knock out my day and have a really great workout. Definitely reccomend this product!

  • Age? 21+
  • Who would you recommend this product to? Anyone needing help losing weight or just wanting that extra kick to help knock out exercise
United States United States

Great steady energy

I enjoy them very well....I do intermetted fasting and it really helps with hunger craving s

  • Age? 18+
  • Who would you recommend this product to? Anyone needed that extra energy in the morning
United States United States


I first found synadrene 3 years ago trying to lose my baby weight. It was made with dmaa back then and I LOVED the every it be have me, it t was amazing. I got three of my girl friends hooked. Unfortunately since dmaa was banned the dmHA makes me feel TOO hot and sick to my stomach I even had a panic attack on it once. I'm really not a panic attack kinda chick . I'm still on the hunt for something that will work for me.

  • Age? 30
  • Who would you recommend this product to? Anyone wanting to try something new. It worked for years, just not anymore.