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Hi-Tech Pharmaceuticals Synadrene 45 Capsules

51 reviews   |  
Original price $69.95
Original price $69.95 - Original price $69.95
Original price $69.95
Current price $34.95
$34.95 - $34.95
Current price $34.95
SKU 811836022360
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For USA orders up to 10lbs.

Hi-Tech Pharmaceuticals Synadrene 45 Caps

If you’re looking for Synedrex, this is the ideal replacement.

Synadrene was developed by Hi-Tech Pharmaceuticals as an alternative to Metabolic Nutrition’s Synedrex. The version of Synedrex that was previously available is being reformulated and it is no longer available to purchase anywhere, or is being sold at a very high price. Chances are we won’t see the reformulated version for a while, and they are most likely removing the active ingredient AMP Citrate. Synadrene is a formula that is closer to the original Synedrex and uses the power of DMHA.

How Does This Compare?

There were 3 different versions of Synedrex in the past. The first version of Synedrex used 1,3 DMAA. The second version just had caffeine. The third and most recent version used AMP Citrate. Synadrene by Hi-Tech is using DMHA, which was like the active ingredient in the original Synedrex. So you’re actually getting a better product that is stronger and closer to the original Synedrex formula.

Benefits & Results

  • Thermogenic fat burning

  • Boosts energy levels

  • Improved mood and focus

  • Stops hunger

  • Power of DMHA

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Questions About Synadrene

Can women use this?

Yes, this product can be used by both men and women. This product is non-hormonal so it is safe for women.

Can I stack this product?

You shouldn’t stack it with other products containing stimulants, but we recommend using it with Thyrene or Hydravax, which are both non/low stimulant. For those wanting to take it pre-workout, you can stack it with non-stimulant pre-workout supplements.

Can I take this with my pre-workout?

Yes, if you are using a non-stimulant pre-workout formula.

Is it gluten free?


How much caffeine is in it?

It is part of proprietary blend, so we are unsure.

How much DMHA is in it?

They do not disclose the amount listed.

How does Synadrene compare to Lipodrene and Lipodrene Hardcore?

The biggest difference between the two is that Lipodrene has ephedra extract. Synadrene does not.

Is there Any Reason Someone Shouldn't Use Synadrene?

If you're sensitive to strong stimulants you may not react well to Synadrene. If you're looking for appetite suppression over energy HydroxyElite or OxyElite Pro may be better options for you. If you're sensitive to Yohimbine you may not want to take Synadrene. You should also consult with your doctor if you are pregnant, nursing, or on other medications. 

Directions & Dosage

Hi-Tech Pharmaceuticals recommends that you start by taking one capsule per day. Take on an empty stomach. Once you know how you respond to one capsule, you can move up to 3 a day if you wish. The best results will be seen when conforming to a diet and exercise program. You should also make sure to get an adequate amount of rest each night. Do not take Synadrene within 4 hours of when you go to bed.


Synadrene is a very strong weight loss supplement, and you should not stack it with any other stimulants. There are other products it can be stacked with:

  • Thyrene - This is a product that can improve thyroid function to promote weight loss and a fast metabolism.

  • Hydravax - This is a diuretic that can help with excess water weight and stop bloating. You will see more definition and get results easier.

What Are the Active Ingredients in Hi-Tech Synadrene?

  • Caffeine - Energy, Appetite Suppression, Focus and Thermogenesis
  • Green Tea Extract - Energy, Appetite Suppression & Thermogenesis
  • DMHA - Decrease in Appetite, Increase in Focus, Increase in Energy
  • Walnut Extract - DMHA from Nature
  • Sulbutiamine - Nootropic, Provides Focus and Energy
  • Sandalwood Extract - Supports Muscles
  • Yohimbe Extract - Clean Energy & Increased Thermogenesis
  • Alpha Lipoic Acid - Powerful Antioxidant and Weight Loss Ingredient
  • Poly Thyronine - Increased Metabolism & Curbs Cravings

Ingredients & Supplement Facts

Servings Per Bottle: 45
Serving Size: 1 Capsule

Vitamin B3 (as Niacin): 20mg
Vitamin B6 (as Pyridoxine HCL): 4.25mg
Vitamin B12 (as Cyanocobalamin): 100mcg
Chromium: 175mcg

Synedrex Formulated Weight Loss Solution Blend: 815mg

Caffeine Anhydrous: *
Green Tea Extract (leaves) *
2-Aminoisoheptane HCL *
Walnut Extract (bark)
Sulbutiamine: *
Sandalwood Extract: *
Yohimbine Extract: *
Alpha Lipoic Acid: *
Poly-liodo-Thyonine: *

Other Ingredients: DiPotassium Phosphate, MCMC, Silicone Dioxide, Magnesium Stearate, Titanium Dioxide, FD & C Blue 1, Red 40, Ti02, Gelatin

Warnings & Side Effects

Do not exceed the recommended dose. This product should only be used by healthy adults at least 21 years old. Do no use if pregnant or nursing, or if you are at risk of, or being treated for diabetes, liver problems, prostate enlargement, anxiety, depression, seizure disorder, stroke or high blood pressure. Consult your health care professional before using any dietary supplements.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, cure, diagnose, or prevent any disease.This product should not be used in place of or as a substitute for recommendations by your healthcare professional. No clinical study has been performed on Synadrene™. These statements are based upon the active ingredients: DMHA, Caffeine, Yohimbine, Sandalwood extract, Sulbutiamine, and green tea extract. WARNING: this product can raise your blood pressure and interfere with other drugs you may be taking. Talk to your doctor about this product.


Lobb A. Science of weight loss supplements: compromised by conflicts of interest?. World J Gastroenterol. 2010;16(38):4880-4882. doi:10.3748/wjg.v16.i38.4880

Huntington MK, Shewmake RA. Weight-loss supplements: what is the evidence?. S D Med. 2010;63(6):205-207.

Tabrizi R, Saneei P, Lankarani KB, et al. The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2019;59(16):2688-2696. doi:10.1080/10408398.2018.1507996

Alkhatib A, Seijo M, Larumbe E, Naclerio F. Acute effectiveness of a "fat-loss" product on substrate utilization, perception of hunger, mood state and rate of perceived exertion at rest and during exercise. J Int Soc Sports Nutr. 2015;12:44. Published 2015 Nov 25. doi:10.1186/s12970-015-0105-8

Warning Concerning California Residents:

This product may contain chemicals known to the State of California to cause cancer and birth defects or reproductive harm.

Customer Reviews
4.7 Based on 51 reviews
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Filter Reviews:
United States United States
Hit or miss

Some bottles are better than others..

  • Who would you recommend this product to? Anyone
  • Age? 25 and up
United States United States
great product

love this product, helps appetite and burn more fat while working out great energy

  • Who would you recommend this product to? yes
  • Age? 53
Katrina H.
United States United States

I love it! BUT be careful. I only use one per day because anything else will hav me up all night. I appreciate the fact it doesnt make me feel jittery BUT it does help with cravings. Synadrex had me SICK! So glad I found Synadrene. I'm about to order another bottle now!

  • Who would you recommend this product to? someone who has a clean diet but needs help to cut fat
  • Age? 30 and above
United States United States
Great supplements

Overal,l, great energy and to workout and keep up with my 3 kiddos

  • Who would you recommend this product to? Busy Mom, whose staying in shape
  • Age? 41
Kim F.
United States United States
Energy Booster

I was recommended this product by my ex boss who both him and I used to take Zenadrine years ago when it was very strong. Since then I couldn't find a product similar until he told me about Synadrene. It gives me all the energy I need and more, creates thermal heat the keeps me burning fat and suppresses my appetite which is a plus. It actually boosts my mood as caffeine has that affect on me. I have lost 18 lbs so far without struggling with hunger and low energy to exercise. I definitely recommend it if you require energy to get you through your work outs and need assistance with controlling your appetite.

  • Who would you recommend this product to? Definitely
  • Age? 46
United States United States

Hi! Is it possible for me to trade my bottle of Synadrene for a bottle of Stimerex? I have a trial bottle of Stimerex that I'm loving!!! The seal has not been broken. I just need to switch products. Thanks so much!

  • Who would you recommend this product to? everyone
  • Age? 30 and above
Chrissy H.
United States United States
My fave

First off, this is a great company. They are always stocked and get orders out ASAP. I’ll never order anywhere else. Second, I love synedrene. It’s the most effective burner. One in the am before workout and I’m good for the rest of the day.

  • Who would you recommend this product to? Anyone familiar with burners
  • Age? Anyone active.
United States United States
Great prices and Products!

Love this product. Great energy, focus and appetite suppression. No jitters.

  • Who would you recommend this product to? Adults looking to lose a few pounds, lose fat and gain every and focus.
  • Age? 42
United States United States
Synadrene is exceptional

Product delivers the results it claims

  • Age? 47
  • Who would you recommend this product to? Anyone wanting an effective metabolic supplement
United States United States
Fast service, great price

I had no problem ordering this item. It was shipped fast Thank you

  • Age? 30
  • Who would you recommend this product to? Students
Lisa K.
United States United States
Hi -Tech Pharmaceuticals Synadrene

It helps my cravings a lot.

  • Age? 55
  • Who would you recommend this product to? Anyone who needs to control there appetite
United States United States
Great price for great pills

They work amazing

  • Age? 24
  • Who would you recommend this product to? Yes
Shannon H.
United States United States

Love the energy it gives me. I'm not jittery and it curbs my appetite. Helps me knock out my day and have a really great workout. Definitely reccomend this product!

  • Age? 21+
  • Who would you recommend this product to? Anyone needing help losing weight or just wanting that extra kick to help knock out exercise
United States United States
Great steady energy

I enjoy them very well....I do intermetted fasting and it really helps with hunger craving s

  • Age? 18+
  • Who would you recommend this product to? Anyone needed that extra energy in the morning
United States United States

I love this product is Amazing! I work at Amazon and it's a fast pace company and I take one half of a pill which last me all day I even have co workers taking it! It's amazing you have to get a bottle and see for yourself.

  • Age? 30
  • Who would you recommend this product to? Everyone
United States United States

It's great! My Abs are showing again.

  • Age? 51
  • Who would you recommend this product to? People who want to get Cut.
United States United States
Good stuff

This is a fat burner for the experienced, I recommend taking it in the AM as I feel it lasts for a good part of the day. At first you feel the jitters/high from it but after the 3rd straight day the jitters are not as prominent. Great appetite suppressant, I only eat because I feel I have to. I saw results in a week. I exercise regularly & eat fairly healthy. I still live life with cheat days but with synadrene those cheat days are far, few & in between.

  • Age? 20-40’s
  • Who would you recommend this product to? Experienced fat burner consumers
United States United States
These items are amazing. If

These items are amazing. If u work out and take this to amazing results.

  • Age? 59
  • Who would you recommend this product to? Anyone
michael S.
United States
Awesome product

Very good and better then expected

  • Age? 18 and older
  • Who would you recommend this product to? To anyone that needed extra energy
United States
Great product

Synadrene gives me de energy I need for my cardio and exercise. I’m the kind of person that doesn’t sweat that much and whit this product I sweat a lot .

  • Age? 53
  • Who would you recommend this product to? Yes